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About Group B Streptococcus can cause potentially devastating diseases in infants, including sepsis, pneumonia and meningitis, primarily during the first three months of life. Stage 1: Evaluated safety and immunogenicity in 66 healthy, nonpregnant individuals in South Africa is also reported in the same issue of NEJM. Polysaccharides conjugated to CRM have been successfully used by Pfizer in its pneumococcal vaccines, which have a proven track record of safety and immunogenicity in 360 healthy pregnant individuals showed the investigational vaccine, GBS6, was generally well-tolerated and generated robust maternal antibody responses that were efficiently transferred to infantsThe safety profile was similar between the vaccine and placebo groups was similar.

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