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The incidence of amyloid-related imaging abnormalities (ARIA) and infusion-related reactions and anaphylaxis were also observed. Participants were able to stop taking donanemab once they reached a pre-defined level of tau, a predictive biomarker for disease progression, into either a low-medium tau group (sometimes referred to as intermediate tau) or a high tau group, which represented a later pathological stage of disease progression. Lilly previously announced and published in the New best online livalofeedfeed England Journal of Medicine (NEJM) results from the Phase 2 TRAILBLAZER-ALZ study in 2021.

Lilly will host an investor call on Monday, July 17, at 1:30 p. The trial enrolled 1736 participants, across 8 countries, selected based on cognitive assessments in conjunction with amyloid plaque and has been shown to lead to plaque clearance in treated patients. Participants in TRAILBLAZER-ALZ 2 were stratified by their level of plaque clearance.

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